The Protandim Story
Watch the original ABC Primetime investigative report that sparked the activation movement — a look at how Protandim® Nrf2 Synergizer® challenged what we thought was possible in human aging.
Protandim
NRF2 Synergizer
Switch
NRF2 pathway
(Regulates antioxidant and detoxification defense systems)
Benefit
- Reduces oxidative stress*
- Supports cellular detoxification*
- Helps maintain a balanced inflammatory response*
- Protects against environmental stressors*
- Supports healthy aging and overall wellness*
NRF2 is your master switch for cellular defense—helping your body stay resilient, balanced, and strong.
Supplementation vs Activation
Each antioxidant molecule from dietary sources eliminate just one free radical. It’s not possible to consume enough to measurably lower oxidative stress.
To neutralize 1,000,000 free radicals you would have to consume: 400 oranges daily, 500 cups of broccoli daily, 110 cups of blueberries, 120 vitamin c tablets daily.
Your body produces trillions of free radicals daily! It’s not possible to fight the onslaught of cellular damage unless you consumed thousands of these antioxidant rich foods/vitamins.
Each molecule of Superoxide Dismustase – just ONE of the enzymes Protandim NRF2 activates has the ability to neutralize 1,000,000 free radicals per second, 24 hours a day, in every cell of your body for the life cycle of the enzyme. Protandim NRF2 reduces oxidative stress in everyone by an average of 40% in 30 days. No other anti-aging or antioxidant supplement can come close to matching Protandim’s power!
Activating your cells to MAKE 300% more glutathione will neutralize One Million Free Radicals. Every Second. Every Day.
The Evolution of Activation & the Research Behind Nrf2
Understanding How Protandim Tunes Your Genes Into Balance…
Dr. McCord explains how Nrf2 activation influences genetic expression — the science of nutrigenomics that helps your body respond and adapt at the cellular level.
Studies on Protandim Nrf2 Synergizer®
What Does “Peer-Reviewed” Mean?
A peer-reviewed study is a research article written by experts and then carefully evaluated by other professionals in the same field before it’s published. This process helps ensure the research is accurate, credible, and of high quality.
Independent studies on Protandim have been carried out by many prestigious institutions, including:
Is my (health concern) linked to oxidative stress?
To research, simply go to PubMed.gov and type in “Oxidative Stress + Health Issue” (ie: Oxidative Stress Cancer, Oxidative Stress Diabetes) etc. Click on the buttons below to go directly to PubMed.gov and view studies on Oxidative Stress, Protandim NRF2 and NRF2.
Protandim
NRF1 Synergizer
Switch
NRF1 pathway
(Supports mitochondrial biogenesis and energy production)
Benefit
- Supports healthy mitochondrial function*
- Increases cellular energy production*
- Promotes healthy aging and vitality*
- Helps improve cellular metabolism*
- Supports brain, heart, and muscle function*
NRF1 is the power switch that helps your cells produce more energy to function at their best.
Synergistic Science
Why These 3 Pathways Work Better Together
Each Protandim Synergizer targets a unique cellular pathway—NRF2 for defense, NRF1 for energy, and NAD for longevity. When activated together, they form a powerful network that supports your body’s natural ability to repair, renew, and perform at its best.
It’s not about taking more supplements—it’s about flipping the right switches at the cellular level, in the right order, every day.
Together, these three switches help your body activate its full potential for healthy aging and performance.