The Protandim Story
Watch the original ABC Primetime investigative report that sparked the activation movement — a look at how Protandim® Nrf2 Synergizer® challenged what we thought was possible in human aging.
Protandim
NRF2 Synergizer
Switch
NRF2 pathway
(Regulates antioxidant and detoxification defense systems)
Benefit
- Reduces oxidative stress*
- Supports cellular detoxification*
- Helps maintain a balanced inflammatory response*
- Protects against environmental stressors*
- Supports healthy aging and overall wellness*
NRF2 is your master switch for cellular defense—helping your body stay resilient, balanced, and strong.
The Evolution of Activation & the Research Behind Nrf2
Understanding How Protandim Tunes Your Genes Into Balance…
Dr. McCord explains how Nrf2 activation influences genetic expression — the science of nutrigenomics that helps your body respond and adapt at the cellular level.
Protandim
NRF1 Synergizer
Switch
NRF1 pathway
(Supports mitochondrial biogenesis and energy production)
Benefit
- Supports healthy mitochondrial function*
- Increases cellular energy production*
- Promotes healthy aging and vitality*
- Helps improve cellular metabolism*
- Supports brain, heart, and muscle function*
NRF1 is the power switch that helps your cells produce more energy to function at their best.
Synergistic Science
Why These 3 Pathways Work Better Together
Each Protandim Synergizer targets a unique cellular pathway—NRF2 for defense, NRF1 for energy, and NAD for longevity. When activated together, they form a powerful network that supports your body’s natural ability to repair, renew, and perform at its best.
It’s not about taking more supplements—it’s about flipping the right switches at the cellular level, in the right order, every day.
Together, these three switches help your body activate its full potential for healthy aging and performance.